Monday, 29 March 2021

February Phytochemicals - Chemistry of the herb Rosemary

Happy #PhytochemicalFriday! Today: tanshinones - diterpenoid compounds from medicinal herb Salvia miltiorrhiza (Red shage, or "danshen") that have rather unique chemical structures. A recent study reports genes involved in the synthesis of these compounds

Happy #PhytochemicalFriday! Today: kauniolide, a sesquiterpene with action against prostate cancer, mycobacteria, and parasites. This compound is found in a variety of asters (including chicory, Cichorium intybus) and its biosynthesis includes remarkable P450 action.

Happy #PhytochemicalFriday! Today: carnosolic acid and carnosol - phenolic diterpenes from rosemary and sage (Lamiaceae). Apart from their interesting structures, these compounds are antioxidants used in food products ("extracts of rosemary") and may have anti-cancer activity.

January Phytochemicals - The chemistry of oatmeal baths

Happy #PhytochemicalFriday and #HappyNewYear2021! Today: hederagenin, a triterpenoid from English ivy (Hedera helix) that is used as a biopesticide (HeadsUp Plant Protectant) to help prevent fungal growth, bacterial growth, and viral plant diseases, including white mold.

#PhytochemicalFriday! Today: deguelin - a flavonoid found in some members the bean family (Fabaceae, e.g. Lonchocarpus. Though found in nature, it's highly toxic to fish & not considered environmentally safe if used on a large scale. It's also under study as a chemotherapeutic!

Happy #PhytochemicalFriday! Today: kaempferol - a bitter-tasting compound that is found in a wide variety of fruits and vegetables, particularly capers - the flower buds of Capparis spinosa (Brassicales). Kaempferol is an antioxidant and features in many traditional medicines.

Happy #PhytochemicalFriday! Today: avenanthramides - phenolic alkaloids from oats (Avena sativa). These anti-itch compounds are abundant in colloidal oatmeal - the reason oatmeal baths can help provide relief from, for example, chicken pox!

Thursday, 7 January 2021

December phytochemicals - the flavor of cinnamon

We made it to #PhytochemicalFriday! Today: phyllodulcin - a coumarin found in several Hydrangea species (incl. macrophylla, shown here). It is hundreds of times sweeter than sugar. Several synthetic organic routes to this compound are known... but biosynthesis is unknown!

Happy #PhytochemicalFriday! Continuing the theme of molecules >100 times sweeter than sugar (thanks @TunnicliffeRoss!), let's look at mogroside V - a triterpenoid glycoside from Siraitia grosvenorii (Cucurbitaceae). A sweetener Asia for 100s (if not 1000s) of years - amazing!

Happy #PhytochemicalFriday! Raise a glass of #Christmas cheer to cinnamaldehyde. Isolated from bark of Cinnamomum verum (the cinnamon tree), this small, simple molecule underlies the cinnamon flavor and is a favorite in gum, beverages, and cereals - it can even repel mosquitos!

Wednesday, 6 January 2021

November Phytochemicals - Another month, another sweetener

Happy #PhytochemicalFriday! Today: trilobatin, a compound from apple leaves (Malus domestica) with potential as a plant-based low-calorie sweetener. A new report in @PlantPhys ( describes the reconstruction of trilobatin biosynthesis in tobacco. So cool!

Happy #PhytochemicalFriday! Today: momilactone B - a diterpenoid produced in Oryza sativa (rice) roots. This compound is allelopathic - it's able to inhibit the growth of plants competing with its maker. Its biosynthetic pathway was recently discovered (!

Tuesday, 5 January 2021

October phytochemicals - Inconceivable!

Happy #PhytochemicalFriday! Today: lycorine, a toxic alkaloid (a nitrogen-containing compound) found in daffodils and some lilies (such as Clivia miniata, Amaryllidaceae). It seems to interfere with protein synthesis if ingested - i.e. don't confuse daffodil bulbs with onions!

Today, iocaine - an odorless, tasteless, plant-based powder from Australia that dissolves instantly in liquid and is among the more deadly poisons known to man. At least one can build up an immunity to it! Happy 33rd birthday to The Princess Bride, and happy #PhytochemicalFriday!
#PhytochemicalFriday! Eugenol, a phenylpropene with a pleasant, spicy scent: the main aroma compound in cloves (Syzygium aromaticum buds). Experience it by lighting a festive autumn candle or have your dentist mix it with zinc oxide to make a tooth filling. Thanks @nicole_groth_!